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AMMASI PERIASAMY, Ph.D.
Professor Center Director, W.M. Keck Center for Cellular Imaging Email: ap3t@virginia.edu Office: (434) 243-7602 Lab: (434) 982-4869 Fax: (434) 982-5210 Address: Room 064, Gilmer Hall, Department of Biology, University of Virginia, Charlottesville, VA 22904 |
| A key area of our research is focused on the use of advanced light microscopy to study/monitor various biological and clinical imaging ranging from a single cell to single molecule in living cells and tissues. Recently, we developed a steady state, confocal, multiphoton, and FLIM based Forster (fluorescence) resonance energy transfer (FRET) imaging system for protein localization in living specimen. The important aspect of the FRET-work is the development of a software package to remove the spectral bleed-through, fluorophore expression level variation and estimate the nanometer (1-10 nm) distance between the protein molecules in living cells and tissue for various light microscopy techniques for any combination of fluorophore pairs. Dr. Periasamy is an internationally recognized expert in advanced microscopy techniques, particularly in the area of molecular imaging in living cells and tissue. He has published over 120 articles in refereed journals and book chapters. Dr. Periasamy has edited three books, Chairperson (since 2001) in organizing an annual International conference on Multiphoton Microscopy in the Biomedical Sciences through SPIE and runs an annual workshop (since 2002) on FRET Microscopy at the University of Virginia, Charlottesville during March. |  |